Abstract

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Abstract

Comparison of Treatment Outcomes among Tuberculosis Pa-tients with HIV and Without HIV Infection in a Metropolitan City

Author:Madhavi Kamble, Yasmeen K. Kazi

Keywords:Tuberculosis, DOTS therapy, HIV infection, treatment outcome. "

Type:Original Article

Abstract:"Background: Tuberculosis (TB) is a major public health problem. Along with HIV infection, it forms a dead-ly combination and those with these diseases are seen to have unfavour-able outcomes. Objectives: 1)To study the clinical profile of TB patients with HIV and without HIV co- infection. 2) To find the treatment outcome among the groups. 3) To compare treatment outcomes of patients between the groups. 4) To assess associated fac-tors influencing treatment outcome in both groups. Methodology: The study group in-cluded sero positive Tuberculosis patients, while the control group in-cluded sero negative Tuberculosis patients. They were enquired about their demographic profile, socio-economic status, past and present TB history including their treatment details and treatment outcome. Ad-ditional information regarding the basic CD4 count diagnosis and An-ti-Retroviral Therapy (ART) was col-lected from the study group. Important Findings: Tuberculosis was more commonly seen in lower socioeconomic group, less educated and economically most productive group. Common symptom seen was fever, cough and weight loss. More prominent signs and symptoms were seen in seropositive patients. Weight gain was more significant in the control group. Treatment out-come was favourable among sero negative patients. Conclusion: Treatment outcome of tuberculosis patients on DOTS reg-imen depends on the HIV status of the patient. "