All Issues >> 2019 >> Issue-10


A Clinico-Epidemiological Profile of HIV Infected Children Attending ART Centre: A Hospital Based Study

Author:Raghavendra Nagaraju, Rachgonda Gurupada Viveki

Keywords:HIV, Children, ART, Opportunistic infection, Clinical stage, CD4 count

Type:Original Article

Abstract:"Introduction: The socio-demographic characteristics of children with Human Immunodefi-ciency Virus (HIV) infection are dif-ferent than the other children of the same age. HIV infection has been studied extensively in adults but pediatric age group is relatively new field. Objectives: To study the socio-demographic profile, clinical spec-trum and its association with im-munodeficiency among HIV infect-ed children. Methodology: The study was con-ducted among HIV positive chil-dren aged 0-14years, attending ART Centre of Belagavi Institute of Medi-cal Sciences (BIMS) Hospital, Bela-gavi. Socio-demographic infor-mation was collected, clinical pa-rameters were assessed and CD4 count was recorded. Results: The study included 180 HIV infected children (112 boys, 68 girls). Prevalence of orphan hood was 73.3%. The prevalence of op-portunistic infection was 42.2% with Tuberculosis (17.3%) being the most common opportunistic infec-tion. Majority of the study partici-pants (45.0%) were in WHO clinical stage I followed by stage II (23.9%), stage III (19.4%) and stage IV (11.7%). Immunodeficiency was seen in 42% of them. Clinical stag-ing of the study participants was significantly associated with pres-ence of opportunistic infections and immunodeficiency. Conclusion: High prevalence of or-phan-hood might lead to significant health consequences. Opportunistic infections increased with immuno-deficiency. "